This is taken from the following site
http://www.oda.state.ok.us/main/srvs/agform/checkmite.pdf

"Do not treat more than twice a year for varroa mites nor more than four
times a year for the

small hive beetle.

For Varroa Treatment - To control varroa mite, remove honey supers before
application of

CheckMite+ Strips and do not replace until 14 days after the strips are
removed. Use

one strip for each five combs of bees in each brood chamber (Langstroth deep
frames or

equivalent in other sizes). Hang the strips in separate spaces between the
combs as near the

center of the bee/brood cluster as possible. If two deep brood chambers are
used for the

brood nest, hang the CheckMite+ Strips in both the top and bottom brood
chambers. Treat all

infested colonies within the yard. The treatment is most effective when
brood rearing is lowest.

Effective control may be achieved by treating hives in the spring before the
first honey flow and

in the fall after the last honey flow. For maximum efficacy leave the strips
in the hive for at least

42 days (six weeks). Do not leave the strips in hive for more than 45 days.
Do not treat

more than twice a year for varroa mites. Honey supers may be replaced 14
days after

the strips are removed.

For Small Hive Beetle Treatment: To control the small hive beetle, remove
honey supers

before the application of CheckMite+ Strips and do not replace until 14 days
after the

strips are removed. Prepare a piece of corrugated cardboard approximately
4x4 inches by

removing one side. Remove one CheckMite+ Strip. Cut strip in half crossways
and staple the

two pieces to the corrugated side of the cardboard. Tape over the smooth
side of the

cardboard (the side opposite the strips) with duct tape, shipping tape or
similar tape to prevent

the bees from chewing and removing the cardboard. Or use one sided plastic
corrugated

sheets. Place cardboard as near the center of the bottom board as possible
with the strips

down. Make sure the bottom board is clean and the strips lay flat on the
bottom board. For

maximum efficacy leave the strips in the hive for at least 42 days (six
weeks). Do not leave

the strips in hive for more than 45 days. Do not treat more than four times
per year

for the small hive beetle. Honey supers may be replaced 14 days after the
strips are

removed."