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Subject:	Re: Edema- blood protein levels (long)
From:	"Torres-Marco, Olyenka D." <[log in to unmask]>
Reply To:	Lactation Information and Discussion <[log in to unmask]>
Date:	Mon, 22 May 2006 15:54:36 -0500
Content-Type:	text/plain
Parts/Attachments:	text/plain (40 lines)

In reply to Jane's questions about nutrition, albumin, pre-albumin and how they influence fluid status. Briefly:
Albumin does regulate fluid in the intravascular space, and it does drop from malnutrition and excessive IV fluids resulting in fluids shifting to the extra-vascular space (3rd spacing). Unfortunately, nutrition cannot fix the problem of excessive IV fluids, the kidneys just have to get to work.
Albumin has a half life of about 20 days, so eating protein would not change your albumin levels fast enough to make a difference. The albumin level will go back to normal once the extra fluids are cleared by the kidneys - not vice versa unless IV albumin is given.
Pre-albumin is the nutritional lab of choice because it has a much shorter half life and is not affected by hydration like albumin is, so you can detect nutritional (energy and protein) deficiencies and repletion within a few days. Albumin on the other hand takes a month or so to recover from a nutritional deficiency.

So, unfortunately, nutrition does not help us here.

PS. On a previous post I spoke about the Registered Dietitian vs. the nutritionist. I forgot this is an international forum, and RD is a credential available mostly in US. My apologies to the other nutrition professionals, I truly meant to say that you should get your nutrition info from a professional in that field, whatever that means where you are practicing.
Daniela Torres Marco MS, RD.
Pediatric Clinical Dietitian
Texas Children's Hospital
6221 Fannin St MC-2-3521
Houston, TX 77030
[log in to unmask] <mailto:[log in to unmask]>

This information is privileged and confidential pursuant to Texas Health & Safety Code sections 161.031 - 161.033 and Texas Occupations Code section 160.007 and or T.R.C.P. 192.5.

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