A question I have often discussed with other animal researchers: why do lab mice have seasonal breeding cycles when kept in climate controlled facilities? The usual answer is that they are programmed to an annual cycle but no one knows what the cue is. An alternate explanation is that in spring the air smells different from winter (floral odors, etc.) even though it passes through filters. I lean toward the annual cycle, but again -- don't know the cue. It could be gravitational, or solar radiation.

PLB

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