Dave says:

   If they are turned upside down during the wing development, they will not
develop normally. A queen that can't fly, cannot mate.

Does anyone have any hard evidence for or against this?  We know queen
breeders who take care never to tip a queen cell on its side.  Others
routinely lay the cells out on a counter on their sides.  One major breeder
just tosses them into a bag, any old orientation.  All seem to be able to
produce healthy queens.

This falls into the same type of debate as to the fragility of the queen on
the comb.  Some of our commercial guys leave any queen that is laying well
(good pattern), regardless of what she looks like.  Some remove any queen
with a missing leg (yet one of the strongest queens that I have ever
observed was missing a hind leg).  Others will immediately kill any queen
who rolls over on her back while on the comb (say from rough handling of
the frame or a gust of wind).

Yet, I know several package producers who shake bees into a box lined with
queen excluders.  Don't even look to see if she is on the frame being
shook.  After shaking a hive body full of frames, they gather around, look
for her, lift her out on their hive tool, and place her back in their own
hive.

According to the notion that she is useless if she falls on her back, how
do you explain the survival and continued productivity of queens banged out
of hives into shaker boxes?  Also, in MD, I saw beekeepers banging packages
on the ground before pulling out the feeder can and the queen.  Seems to me
that she got an awful pounding in her little cage when the beekeeper
pounded the package to throw all of the bees to one end.

Something to think about.