Technically, you can never kill a virus since they are inside cells unless you use a protease inhibitor like Paxlovid for Covid -19. Still, suitable chemicals can destroy the infectious agents or virions outside cells under the right conditions, which brings up the hive components' role in transmission. I talked with Jay Evans about hive components, and his opinion is that some small amounts of virions may be transmitted but not enough to cause DWV pathology on their own. Anecdotally we know this since we reuse equipment without an issue.
I haven't seen any research on an organic acid that can destroy a naked icosahedral capsid, but maybe others have.
Using OA or Formic acid kills mites, so you can say it stops transmission, but a high viral load, that causes pathology is intracellular and cannot be cleared with any agent I'm aware of except for the colony's death.
If there is interest in the disinfection of hive surfaces, the research listed below on Norovirus is likely relevant to DWV since they both have tough naked capsids, and the durable protein structure can remain viable on surfaces for a long time. Norovirus infects hundreds of millions of us yearly and kills about 200,000. So the food and cruise industries want the best way to disinfect. Since DWV and Norovirus lack a lipid envelope, disinfectants improperly used can just be theater. On the surface tested, the two agents most active against virions were quats, mentioned earlier by Pete, and ethanol but not just any ethanol. The ethanol needed to be in a high-pH solution- the one tested was in the 12.8 ph range. The high alkalinity appeared responsible for quickly disassembling the capsid - about 30 seconds. Quats, although effective, needed thirty minutes to work.
>The Efficacy of Commercial Surface Sanitizers against Norovirus on Formica Surfaces with and without Inclusion of a Wiping Step
> https://journals.asm.org/doi/10.1128/aem.00807-22
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