> If you could swamp your locale with resistant stock... 

Or use an island.

https://youtu.be/NUpApdL49Rc

or another island

https://youtu.be/RqFJAFqYzTw

Curiously, neither one is far enough away from the mainland to assure a 100% water barrier to bees.

But, Dr. Adrian Wenner (UC Santa Barbara) famously tried to eliminate honey bees from Santa Cruz island, which is 6 miles offshore, well beyond reasonable bee flight range over water, and this took well over a decade.

Another possibility might be in the managed pine forests north of Mt. Katahdin and Baxter State Park in Maine.  Vast pine monocultures are grown there, and pines don't tend to offer cavities to bees like oaks do (see the 1976 Morse-Seeley "Nests of bees" paper, which says "the most common genus, Quercus (Oak), predominated only slightly...")

  

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