Thanks Adony for your post after our discussion on Sunday. I always had 
trouble comparing the results of these two papers.  Time has come to 
revisit the fumagillin application methods for various management systems 
and climatic conditions.
Harrison was wondering why dusting is good for tylosin and Oxy Tet 
application why not fumagillin. Available published data have not shown a 
better mean for applying dusting that will produce good efficacy. I might 
suggest that too many factors could be involved i.e. the type of pathogen, 
 the mode of action of fumagillin, fumagillin half life, etc.  And the 
most important factor is brood diseases vs adult diseases. The effects of 
these variables should be considered in any study. The most interesting 
studies about fumagillin are coming from the medical sciences. Recent 
studies showed that Fumagillin suppresses HIV-1 infection of macrophages 
through the inhibition of Vpr activity.  
Time has come to revisit this issue and I am sure that there are many 
studies are underway to address these issues.

 
 
Medhat


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