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Subject:
From:
"Nice, Frank (NIH/NINDS)" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Fri, 18 Apr 2003 09:14:24 -0400
Content-Type:
text/plain
Parts/Attachments:
text/plain (23 lines)
Micromedex lists hydroxychloroquine use in breastfeeding as controversial.
Hydroxychloroquine was excreted into breast milk in 2 of 2 mothers using
this drug.  Concentrations were 344 and 1,424 ng/mL, respectively, with milk
to whole blood rations of 0.48 and 0.85, respectively.
The article that the doctor's may be citing is:
Costedoat-Chalumeau N, Amoura Z, Aymard G, et al. Evidence of transplacental
passage of hydroxychloroquine in humans.  Arthritis Rheum 2002; 46 (4):
1123-4.
I do NOT have a copy of the article.
Frank J. Nice, DPA, CPHP

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