Br J Nutr. <javascript:AL_get(this, 'jour', 'Br J Nutr.');> 2010
Jan;103(2):235-42. Epub 2009 Aug 25.
Supplementation of DHA but not DHA with arachidonic acid during pregnancy
and lactation influences general movement quality in 12-week-old term
infants.
van Goor SA<https://mail.google.com/pubmed?term=%22van%20Goor%20SA%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>,
Dijck-Brouwer DA<https://mail.google.com/pubmed?term=%22Dijck-Brouwer%20DA%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>,
Doornbos B<https://mail.google.com/pubmed?term=%22Doornbos%20B%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>,
Erwich JJ<https://mail.google.com/pubmed?term=%22Erwich%20JJ%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>,
Schaafsma A<https://mail.google.com/pubmed?term=%22Schaafsma%20A%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>,
Muskiet FA<https://mail.google.com/pubmed?term=%22Muskiet%20FA%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>,
Hadders-Algra M<https://mail.google.com/pubmed?term=%22Hadders-Algra%20M%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>
.
Laboratory Medicine, University Medical Center Groningen, Internal postal
code EA22, PO Box 30.001, 9700 RB Groningen, The Netherlands.
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DHA and arachidonic acid (AA) are important for neurodevelopment. A
traditional neonatal neurological examination and the evaluation of general
movement quality are sensitive techniques for assessing neurodevelopment in
young infants. Mildly abnormal general movements at 3 months have been
associated with a non-optimal current brain condition. We investigated
whether supplementation of DHA during pregnancy and lactation influences the
infant's brain development and whether additional AA modulates this effect.
Healthy women were randomly assigned to DHA (220 mg/d, n 42), DHA+AA (220 mg
each/d, n 41) or control (n 36), from about week 17 (range 14-20 weeks) of
pregnancy until 12 weeks postpartum.
The control and the DHA+AA groups had approximately comparable dietary
DHA/AA ratios. The standardised neonatal neurological examination was
carried out at 2 weeks. General movement quality was assessed at 2 and 12
weeks. Neither DHA alone nor DHA+AA influenced outcomes in the traditional
examination.
General movement quality of infants in the DHA group was lower than that of
infants in the other two groups, especially at 12 weeks: 61 % of the infants
in the DHA group showed mildly abnormal general movements compared with 31 %
in the control group (P = 0.008) and 34 % in the DHA+AA group (P = 0.015).
We conclude that general movement quality at 12 weeks is sensitive to the
maternal dietary DHA/AA balance.
--
Nikki Lee RN, BSN, Mother of 2, MS, IBCLC, CCE, CIMI
craniosacral therapy practitioner
www.breastfeedingalwaysbest.com
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