>>I notice that the point I have repeatedly made about the OTC resistance 
>>appearing fairly shortly after the banning of sulfa is repeatedly ignored.

> Is this true?   My somewhat defective memory is that sulfa was banned 
> early '80s  and I don't remember any talk of resistance until mid '90s?
Good question.  I can't recall the dates, but your estimate sounds about 
right.

> 10 years is not extremly quickly.

That is not what I claimed.  I said fairly quickly and in the context where 
we don't know

1.) the exact date of the ban

2.) the date that beekeepers actually stopped using it, especially on 
particularly stubborn cases in nurse yards not producing honey and

3.) we do not know the exact date that resistance appeared.

the interlude looks to me to be short in comparison the previous long period 
of antibiotic efficacy while sulfa was in widespread use.

As I recall, the first reports of OTC resistance came from Argentina, then 
Florida.  Some of the history is in our archives at WWW.BEE-L.ORG (Check out 
the new URL)

How long did it take to realise that some AFB was resistant and to 
investigate and report it?  Several years, I suspect.

> And how widespread is this resistance?  Not seeing it here.

It seems to be under control, due to better bees, burning, radiation, and 
the use of Tylosin combined.

In my search for dates I cam up with this gem.    I am too busy to read it 
properly, but it looks good.  Enjoy.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC385787/pdf/jbacter00620-0040.pdf 

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