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Date: | Mon, 9 Nov 1998 12:50:46 -0500 |
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To : Dee
Re : Tricor(fenofibrate)
Fenofibrate is an fibrinic acid derivative that specifically reduces plasma
triglycerides. We have no data on its transfer into human milk, but due to a
99% protein binding, it is likely small.
It is well absorbed orally, and has a very long half-life > 20 hours.
However, morbidity studies with this drug show a greatly increased risk of
death, particularly from cancer and liver disease.
While I theoretically believe that the amounts in breastmilk may be low, the
significantly elevated risk of carcinogenesis in exposed individuals does
not make me comfortable in recommending its use in a breastfeeding mother.
Regards
Tom Hale, Ph.D.
Regards
Tom Hale, R.Ph., Ph.D.
Associate Professor of Pediatrics
http://neonatal.ttuhsc.edu/lact/
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