Subject: | |
From: | |
Reply To: | |
Date: | Sat, 25 May 1996 23:29:11 -0400 |
Content-Type: | text/plain |
Parts/Attachments: |
|
|
Arly,
PKU is autosomal recessive. THe baby would not be affected unless the father
was also a carrier or had PKU.
If dad and mom both had pku, each baby has 100% chance of having PKU.
If dad is a carrier, and mom has pku (or vice versa), each baby has a 50%
chance of having pku, and a 50% chance of being a carrier (heterozygous).
If dad is not a carrier, each child will be a carrier but not affected.
Lawrence states that the amino acid profile of the milk of mothers
with PKU being controlled by diet are normal. I have been able to find
nothing about phe levels in milk of mothers who are not on the phe free diet.
I wonder if the normal baby would be able to convert the phe to tyrosine fast
enough to avoid brain damage? Not an experiment I would want to perform, the
stakes being what they are...
Catherine Watson GEnna, IBCLC (who once considered being a genetic
counsellor) NYC [log in to unmask]
|
|
|