----- Original Message ----- 
From: "Hale, Thomas Wright" <[log in to unmask]>
To: "Alice Martino Roddy " <[log in to unmask]>
Sent: Sunday, May 07, 2006 10:21 PM
Subject: RE: preface page 6, bottom paragraph


Alice:

You are  cetainly correct.  It is the "infants plasma".

Thank you so very much for letting me know.

Tom Hale Ph.D.
Presently in Adelaide Australia...



-----Original Message-----
From: Alice Martino Roddy
To: Hale, Thomas Wright
Sent: 7/05/2006 4:20 PM
Subject: preface page 6, bottom paragraph

I'm reading my new edition and there is something I have a question
about (well, actually there is a great deal I don't understand but. . .
). In the preface, page 6 bottom of the page is this paragraph:

However, once medications transfer into human milk, other kinetic
factors are involved. One of the most important is the oral
bioavailability of the medication to the infant. Numerous medications
are either destroyed in the infant's gut, fail to be absorbed through
the gut wall, or are rapidly picked up by the liver. Once in the liver,
they are either metabolized or stored but often never reach the mother's
plasma.

Should the last sentence read infant's plasma rather than mother's
plasma?

Alice Martino Roddy
"I did the best I knew at the time and if I'd known better, I'd have
done better." Ruth Alderman Tait

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