The dosage recommendation that I provided is the exact dosing schedule use 
by the manufacturer and FDA when the prodeuct was on the market.  I believe 
that both nostrils were used to ensure that an adequate amount of the 
Syntocinon was absorbed.  As anyone who uses nasal sprays knows, sometimes 
as much gets into the nose, also ends up in your throat or running out of 
your nose.
In any case, what is important is to use the amount that works.
Hope this helps clarify the dosage schedule.
Frank J. Nice, DPA, CPHP


>From: "Rachel Myr" <[log in to unmask]>
>To: <[log in to unmask]>
>Subject: Syntocinon nasal spray dosage
>Date: Tue, 22 Nov 2005 13:46:36 +0100
>
>Hi Frank, and everyone else - just to let everyone know that Novartis still
>makes Syntocinon nasal spray which is a prescription drug here in Norway,
>with the exact composition as given in Frank's post.  BUT the dosage is one
>squirt in ONE nostril just before offering the breast or expressing milk.  
>A
>single squirt of the nozzle delivers 4 international units of oxytocin,
>which is forty percent of what many women are routinely given as a bolus in
>third stage of labor, or following delivery of the placenta at cesarean
>section.  Since oxytocin has a half life in the body of less than 3 
>minutes,
>the potential to harm the baby is so close to zero as to be negligible.
>Besides, it isn't bad for them anyway.
>The current price for a 5 ml nasal spray bottle is under 90 Norwegian
>crowns, or about 13 dollars US.  Wish there was a legal way for me to 
>export
>it.  We don't often use it but for mothers who need to start pumping and
>have a hard time letting down their milk to the pump, it helps, and it 
>seems
>to increase volumes taken by the baby in cases of babies with impaired suck
>where they are dependent on more active delivery of milk by the breast.
>
>If the woman uses it in both nostrils every time, she uses it up twice as
>fast and doesn't get any more effect than if she simply sprays it in one,
>and then she can alternate sides to avoid the irritation of the mucosa 
>which
>some women experience.
>
>Cheers
>Rachel Myr
>Kristiansand, Norway, where I don't think I have ever, not once, seen a
>problem with MER which I would attribute to a stressful life - but we have
>**serious** maternity leave too. :-)
>
>

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