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Date: | Sat, 25 Jun 2005 08:54:40 -0400 |
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Hello all!
This was on Medscape. I haven't had the time to read the real article. You
can "join" medscape free of charge to view other article reviews.
I wonder if they differentiated from Type I and Type II diabetes or if they
controlled for family diet when looking at a 2 year old's weight. It would
also be interesting to see how the researchers defined "exclusive"
breastfeeding.
Read on:
Early Breast-Feeding by Diabetic Mothers May Have Long-Term Effect on
Offspring
NEW YORK (Reuters Health) Jun 24 - Late neonatal ingestion of breast milk
and the duration of breast-feeding do not appear to independently influence
the risk of overweight or impaired glucose tolerance in the children of
diabetic mothers, according to researchers. However, breast-feeding during
the first week of life may have a more important influence.
The offspring of diabetic mothers have an increased risk of developing
these two conditions, principal investigator Dr. Andreas Plagemann and
colleagues from Charite-University Medicine Berlin, Germany, note in the
June issue of Diabetes Care. "Recently, we observed that early neonatal
ingestion of breast milk from diabetic mothers may dose-dependently
increase the risk of overweight in childhood."
To investigate, the researchers evaluated 112 children of diabetic mothers
who were breast-fed. Mean age at follow-up was 2.1 years.
"Exclusive breast-feeding was associated with increased childhood relative
body weight (p = 0.011)," the investigators report. "Breast-fed offspring
of diabetic mothers had an increased risk of overweight (odds ratio 1.98)."
A positive relation was observed between breast-feeding duration and
childhood relative body weight (p = 0.004). Duration of breast-feeding was
also positively related to 120-min blood glucose during oral glucose
tolerance test (p = 0.022).
However, all of the associations with late neonatal breast-feeding and its
duration were eliminated after adjusting for the breast milk volume
ingested during the early neonatal period (1st week of life).
Dr. Plagemann's group hypothesizes that the first week after birth is
a "critical period, when exposure to diabetic breast milk may have a
negative long-term influence on risk of overweight and diabetes in
offspring of diabetic mothers. This might have important practical
consequences."
Diabetes Care 2005;28:1457-1462.
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