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Date: | Tue, 1 Mar 2005 20:00:33 EST |
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From the latest Pediatrics:
Late-Onset Septicemia in a Norwegian National Cohort of Extremely Premature
Infants Receiving Very Early Full Human Milk Feeding
Objectives. To investigate the occurrence of and risk factors for late-onset
septicemia (LOS) in a national cohort of extremely premature infants who
received very early full human milk feeding.
Results. Enteral feeding with human milk was initiated within the third day
for 98% of patients, and 92% were receiving full enteral feeding (FEF) with
human milk within the third week. Both high Clinical Risk Index for Babies
scores and an umbilical venous catheter in situ at 7 days of age significantly
predicted LOS. However, the overall most influential risk factor for LOS was
the number of days without establishment of FEF with human milk, with an
adjusted relative risk of 3.7 (2.0–6.9) for LOS if FEF was not established
within the second week of life.
Conclusions. The incidence and case fatality rate of septicemia for this
cohort of extremely preterm infants were lower than values in comparable studies.
The main difference, compared with other studies, was the feeding practice,
and the data suggest that very early FEF with human milk significantly reduces
the risk of LOS among extremely premature infants.
http://pediatrics.aappublications.org/cgi/content/abstract/115/3/e269?etoc
Kathleen Fallon Pasakarnis, M.Ed. IBCLC
Nurturing Family Lactation and Parenting Services
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