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A friend sent this to me. I thought it might be of interest.
Oral Bisphosphonate Therapy for Vitamin D Intoxication of the Infant
Abdullah Bereket, MD and Tulay Erdogan, MD
PEDIATRICS Vol. 111 No. 4 April 2003, pp. 899-901
Department of Pediatrics
Division of Pediatric Endocrinology
Marmara University
School of Medicine
Istanbul 81030, Turkey
Vitamin D intoxication in infancy has serious consequences attributable to acute hypercalcemia and subsequent hypercalcuria/nephrocalcinosis. Current treatments of patients with vitamin D intoxication are unsatisfactory andassociated with prolonged hypercalcemia. We now report the use of oralalendronate sodium in a 3-month-old infant with vitamin D intoxication.Short-term oral alendronate sodium treatment effectively correctedhypercalcemia/hypercalciuria, decreased the duration of hospitalization, and
appears safe in 15 months of observation.
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