I found this and it has a lot of references...

http://www.health-e-learning.com/breasted_web_articles/JustOneBottle/JustOneBottle.pdf

Joylyn

Barb Strange wrote:

> I am working away at my report here and I'm stumped for a reference -- just
> can't find what I'm looking for on PubMed or LACTNET archives.
>
> Every now and then on LACTNET someone will write that ABM impairs gut
> integrity of babies.  I believe this, or at least I would like to believe
> it, because it makes sense.  Problem is, is this really true?
>
> There are studies saying that intestinal permeability is reduced more
> quickly in breastfed babies, as soon as they start breastfeeding, in fact.
> This shows the positive effect of breastmilk.  There are also studies that
> indicate that babies with sensitivity to cow's milk protein show mucosal
> damage which clears once the ABM is removed.  And there are other studies
> finding increased intestinal permeability in ABM-fed children who have also
> experienced GI infections (no coincidence, I'm sure).  Some of the studies
> on necrotizing enterocolitis mention the ameliorating effect of breastmilk
> on that condition, but don't actually point the finger at formula (ie. they
> focus on the addition of a positive rather than on the removal of a
> negative).
>
> But none of this is the same as saying that damage to gut integrity occurs
> in *normal* babies, that is, term babies without sensitivity to cow's milk
> protein or evidence of GI infection.  It might be that ABM fed babies, since
> we know they have more diarrheal incidents, show decreased gut integrity due
> to these GI incidents alone, but it seems that there must be more to it than
> this.
>
> So, does ABM cause decreased gut integrity and/or mucosal damage in normal
> healthy babies?
>
> Thanks,
>
> Barb Strange
>
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