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I did a Hale look up ('97ed) and couldn't find the exact drug you mention.
However, I did find something close (thinking maybe the Pro is a prefix or
something) so , if you think that this is the same drug, this might be useful:
Amantadine
Trade: Symmetrel, Symadine
Uses:Anti-viral
AAP:not reviewed
Amantadine is a unique compound that has both antiviral activity against
influenzeA and is effective in treating Parkinsonian symptoms. Pediatric
indications for prevention of influenza for ages 1-10 are available. Trace
amounts are believed to be secreted in milk although no reports are found.
Adult plasma levels following doses of 200mg daily are 400-900nanograms/mL.
Even assuming a theoretical mik:plasma ratio of 1.0, the average daily dose to a
breastfeeding infant would be far less than 0.9mg, a dose that would be
clinically irrelevant compared to the 4-8mg/kg dose used in 1 year old infants.
Pregnancy Risk Category: C
Adult Concerns:Urinary retention, vomiting, insomnia, depression, confusion,
disorientation, nausea, constipation, vomiting.
Pediatric Concerns: None reported via milk
Drug interactions: May increase anticholinergic effects when used with
anticholinergic orCNS active drugs. Increased toxicity/levels when used with
hydrocholorothiazide plus triamterene, or amiloride.
AHL 1-28 hours
PHL
PK1-4 hours
MW151
Vd4.4
M/P
PB67%
Oral86-94%
pKa10.1
I'm not entirely sure that this is the drug that you are looking for. If it's
not I hope you find it soon.
Tammy Schilling
LLL of Salisbury
"Heidi A. Bingham" wrote:
> Hello Wise Ones <g> ~ I need some information on a med. I searched the
> archives and Hale's site and couldn't turn up anything. Can someone help
> out? I have an inquiry from a mom who writes, "I take Pro-Amatine. This
> constricts my blood vessels to raise my blood
> pressure." Is this med compatible with breastfeeding and if not is there an
> alternative she could try that is? Thanks ~ Heidi
>
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