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Subject:
From:
Chris Hafner-Eaton <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Fri, 16 Feb 2001 20:36:19 -0800
Content-Type:
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FYI:

Cows' milk protein-sensitive enteropathy: an important contributing cause of
secondary sugar intolerance in young infants with acute infective enteritis.
Arch Dis Child 1979 Jan;54(1):39-43   (ISSN: 0003-9888)
Iyngkaran N; Davis K; Robinson MJ; Boey CG; Sumithran E; Yadav M; Lam SK;
Puthucheary SD [Find other articles with these Authors]
The effect of cows' milk protein (CMP) on the mucosal disaccharidases was
investigated in 23 infants with acute infective enteritis. Jejunal biopsies
performed before and after cows' milk provocation were subjected to
histological examination and to mucosal disaccharidase enzyme (lactase,
sucrase, and maltase) analyses. After milk challenge, changes in mucosal
histology were observed in 18 infants, in 17 of them the levels of all 3
mucosal disaccharidases were much reduced. 10 of these infants developed
diarrhoea and, in 6, the stools were positive for reducing sugar. It is
concluded that CMP has a deleterious effect on the jejunal mucosa of young
infants recovering from infective enteritis, so that in the management of
young infants with sugar intolerance secondary to infective enteritis, CMP
and lactose should be excluded from the diet.
   
--Chris Hafner-Eaton, PhD, MPH, CHES, IBCLC    [log in to unmask]
€€€INFANT CUISINE AND MOTHER CARE: LACTATION CONSULTING & PERINATAL CARE€€€

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