Hi, you both posted similar cases in Lactnet and I thought this article
would be useful to you.  Here's the reference and abstract.

J Pediatr Gastroenterol Nutr 1994 Jul;19(1):22-6
Allergic colitis in infancy: clinical and pathologic aspects.
Machida HM, Catto Smith AG, Gall DG, Trevenen C, Scott RB
Department of Pediatrics, University of Calgary, Alberta, Canada.

This study prospectively evaluated 35 consecutive infants who presented
with fresh blood mixed with stools.  The mean age at onset of bleeding was
approximately 4 weeks.  All infants were otherwise asymptomatic and
exhibited normal growth and physical examinations.  None had evidence of a
bleeding diathesis, viral or bacterial enteritis, or necrotizing
enterocolitis. Consent for limited colonoscopy and biopsy was obtained for
34 infants.  Twenty-five had macroscopic colitis and 10 infants had marked
nodular lymphoid hyperplasia.  Thirty-one infants had histopathological
evidence of colitis characterized by a marked eosinophilic infiltrate.
Compared with 19 controls (age, 4.1 +/- 3.6 months) the mean number of
eosinophils per high-power field was greater in the patients with colitis.
Patients with colitis also had an elevated mean absolute peripheral
eosinophil count and a low mean serum albumin compared to control values.
The 31 infants with colitis were receiving solely breast milk (10), cow's
milk formula (9), soya formula (9), breast milk with cow's milk formula
(2), or nutramigen (1) at the time of presentation. Nineteen infants had
rapid resolution of frank bleeding and gradual correction of serum albumin
with dietary change.  While limited colonoscopy and biopsy were useful in
establishing a definitive diagnosis, a low serum albumin and high
peripheral eosinophil count suggested the diagnosis.  Colitis
characterized histologically by >20 eosinophils per high-power field is a
common cause of rectal bleeding in otherwise healthy young infants.
Resolution of bleeding and increase in serum albumin after dietary change
suggest that this is an allergic colitis: however, the pathogenesis of
this disorder needs further clarification.

(I also noticed that there was a new one last month but I haven't read it.
The title is "Gastrointestinal bleeding in infancy and childhood," by Fox
VL.  Gastroenterol Clin North Am. 2000 Mar;29(1):37-66)

Hope this helps.

Ginna Wall, MN, IBCLC, Lactation Services Coordinator
University of Washington Medical Center, Mailbox 356078
1959 NE Pacific Street, Seattle WA 98195
Voicemail: (206)598-6368, Fax: (206)598-7665

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