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Subject:
Infant stomach acid
From:
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Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Thu, 22 Jun 2000 21:15:25 EDT
Content-Type:
text/plain
Parts/Attachments:
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Discussing prilosec (omeprazole), Tom Hale wrote,

<< However, in an acidic mileu, omeprazole is instantly degraded and
destroyed.  Thus none would be absorbed by the infant even if present in
milk.  >>


Is it correct though that infants have (normally) a much less acidic stomach
environment than older people?   I seem to recall Chris H-E posting a while
back that this was why infants are more susceptible to botulism -- because
the spores normally destroyed in the adult stomach acid are not reliably
destroyed in the infant GI tract.

Is this somewhat true?  Very true?  How true would it have to be to make it
still the case that "none" of various drugs  "would be absorbed by the infant
even if present in milk"?

Elisheva Urbas

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