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Lactation Information and Discussion <[log in to unmask]>
Date:
Tue, 19 Jan 1999 15:32:48 -0500
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Lactation Information and Discussion <[log in to unmask]>
Subject:
buprenorphine
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From:
newman <[log in to unmask]>
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To: Françoise Railhet <[log in to unmask]>
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According to Hale:

Protein binding high (96%): That's good
Oral bioavailability low (31%): That's good

"In one patient who received 4 mg/day for withdrawal off other opiates, the
amount of buprenorphine transferred via milk was only 3.28 micrograms/day,
and amount that was clinically insignificant".

Jack Newman, MD, FRCPC

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