As Kerry Clark points out, Mite Solution is not legal to use. I have grave concerns about using unregistered substances in hives. Apistan has been shown to be effective, and as a contact dispersed chemical, a don't worry so much about adulteration of comb, honey, etc. Squirting, pouring, or fumigating with untested substances can lead to contamination of the hive and products. Worse yet, you don't even know whether it truly works. We see lots of beekeepers taking veterinary products, squirting them on cotton balls, carboard, rags, you name it. Dose, means of distribution, effectiveness - all word of mouth and many someone's guess or impression. Do you really save anything by using something that could be harmful to your bees or product and that may or may not control mites? Jerry Bromenshenk [log in to unmask] http://grizzly.umt.edu/biology/bees