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Subject:
From:
Bill Truesdell <[log in to unmask]>
Reply To:
Informed Discussion of Beekeeping Issues and Bee Biology <[log in to unmask]>
Date:
Wed, 5 Dec 2001 14:50:23 -0500
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Aleksander Mihajlovski wrote:

> antibiotic called: Rifampicin.
> Have anyone ever heard of these antibiotic (in human or livestosk contex)?
> Any reference?



Apidologie 32 (2001) 215-222

Screening alternative antibiotics against
oxytetracycline-susceptible and -resistant Paenibacillus larvae

Jan Kochansky, David A. Knox, Mark Feldlaufer and Jeffery S. Pettis

USDA ARS Bee Research Laboratory, Building 476, 10300 Baltimore Avenue,
Beltsville, MD 20705-2350, USA

(Received 16 June 2000; revised 11 December 2000; accepted 15 February
2001)

Abstract
Since resistance of the causative organism of American foulbrood,
Paenibacillus larvae subsp. larvae, to oxytetracycline (OTC) is
becoming widespread in the United States, we began a search for
effective alternative antibiotics. We investigated the sensitivity of
P. l. larvae to 27 antibiotics, which were primarily ones already
registered with the US Food and Drug Administration for agricultural
uses. Bacterial resistance to OTC also conferred resistance to other
tetracyclines, although the level of resistance varied. The most
active antibiotics screened that are currently used in agriculture were
erythromycin, lincomycin, monensin, and tylosin. Rifampicin
was by far the most active antibiotic tested, but since it is used
against tuberculosis, registration of this material for agricultural use
is unlikely.

Hope this helps.
Bill Truesdell

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