>Our data revealed that the expression of nearly 1,400 genes was altered in response to dsRNA-GFP, representing around 10% of known honey bee genes. Expression changes appear to be the result of both direct off-target effects and indirect
downstream secondary effects
Sounds like a disaster to implement with any certainty that the desired results could be achieved. Is it possible that off-target effects are what's hampering Monsanto's RNAi efforts at varroa control?
Bill Hesbach
Cheshire CT
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