PLB
>epidemics in these areas and show that *high population density* and *poor sanitation* cause persistence by not only facilitating transmission of poliovirus but also severely compromising the efficacy of the trivalent vaccine.
Science 17 Nov 2006:
Vol. 314, Issue 5802, pp. 1150-1153
DOI: 10.1126/science.1130388 <
This is not surprizing. It is like chickens and coccidiosis. If a chicken has had a vacination, you do not want to feed them medicated feed or the medicine cause it cancels out the vacination.
Cheers
gww
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