I recently did a search on this (for a book of mine on PND - actually 'recent' is about a year ago so this is not red hot) but my recollection (off top of head) is that oestrogen therapy has been evaulated as treatment for severe PND, but not as a prevention, and that studies are still awaited that will confirm its safety and effectiveness for mild to moderate PND. I did not come across any studies that looked at its effect on bf. I would share Pamela's caution, just on common sense grounds. Giving any hormone at the start of bf is a very big deal indeed, and should be done with trepidation. Heather Welford Neil NCT bfc Newcastle upon Tyne UK