Sorry Cindy this is clinical results, not research based. I don't think anyone has monitored mom's liver functions. Phizer would be the ones to go to for answers. However diflucan is used long-term in people with immun suppression/yeast problems, so Phizer ought to be able to give you some data. Also diflucan has been used in premies and liver function was observed as far as I know. From these two situations I think we extrapolated that it would be OK for healthy moms and/or newborns. Sincerely, Pat in SNJ