Received: from smtp1.globalserve.net (smtp.globalserve.net [209.90.144.2]) by enigma.globalserve.net (8.8.6/8.6.9) with ESMTP id KAA20137 for <[log in to unmask]>; Sun, 18 Jan 1998 10:10:19 -0500 (EST) Received: from 209.90.135.72 (dialin1343.toronto.globalserve.net [209.90.135.72]) by smtp1.globalserve.net (8.8.8/8.8.8) with SMTP id KAA17784; Sun, 18 Jan 1998 10:16:24 -0500 (EST) (envelope-from [log in to unmask]) Message-ID: <[log in to unmask]> Date: Sun, 18 Jan 1998 10:21:48 -0500 From: newman <[log in to unmask]> Reply-To: [log in to unmask] X-Mailer: Mozilla 2.02 (Macintosh; I; 68K) MIME-Version: 1.0 To: Kathleen Bruce <[log in to unmask]> CC: NatJoeFred <[log in to unmask]> Subject: aspirin Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-UIDL: 6df1178f89b06977f378af5581f844de Status: U X-Mozilla-Status: 0000 Dear Dr. Umlauf, The risk of metabolic acidosis in the baby is virtually zero with that dose. There has been one case that I know of where metabolic acidosis has been described in the baby of a nursing mother who was taking, I believe, 2.4 grams of aspirin a day. Furthermore, if I remember the report, the baby was much younger than 6 months. The amount in the milk after a 325 mg dose with a reported M/P for aspirin of 0.03-0.08 is likely to be negligible. I also think the issue of Reye's syndrome is overstated. Jack Newman, MD, FRCPC