Christine: from t hale: omeprazole is a potent inhibitor of gastric acid secretion. the secretion of omeprozole into human milk is unreported but it is likely to be minimal. in rodent studies, high doses(35X) produced decreased weight gain in pups, however comparison to humans in unknown. This drug is not generally recomeened in nursing mothers, but the drug is very safe and has few side effects. capsules are delayed releasee, omeprazole is extremely acid lible. significant quantities may be destroyed in the stomach prior to absorption in the upper intestine. see famotidine or nizaatidine as better choices. P 299 Patricia