Pat: the drug is listed in briggs freeman and yafee.... the aap classifies it as a drug that produces adverse efefects and should be used with caution... does not say not to use. this comes from a sigle instance where the mother eas inserting, rectall 500 mg twice a day. her baby developed diarrhea. in studies with mothers taking oral doeses with from 3 g/day to 500 mg 3 times a day there weere no adverse effects on the infant.... Briggs. p 552. Patricia