I may not be qualified to answer this question, but I would like to share my experience. There are many issues involved in the use of fertiltiy drugs during breastfeeding. The first issue is what effect lactation is having on a woman's fertility and fecundity, lactation itself may be contributing to infertility. The second big unknown is the effects of the drugs if any on the nursing child. The third over- riding issue I have seen is the desire of the mother to not lose the breastfeeding relationship in hopes of conceiving another baby that may never become a reality. The fear of loss is very great in infertile women, especially those who had a long period of primary infertility. The issue of the biological clock is another consideration, many mothers with infertility problems are older and really feel the clock ticking. As a child grows and is nursing less and less, the potential exposure to the drugs in reduced. For instance a 3 year old who nurses twice a day will not receive as much exposure as a six month old exclusively breastfed baby. Many fertility drugs inhibit lactation, clomid and parlodel have been known to dry up milk fast. Taking all of these things into consideration, it has been my experience that some MDs are willing to treat a lactating mother of an older baby (child). I know of several women who conceived on clomid while nursing. In spite of the unknown, but potentially harmful risks, they have used the drugs. I have a beautiful daughter who is an example of this. Cathy