I carry an EpiPen in my briefcase. It was manufactured for Center Laboratories. It delivers a 0.3 mg intramuscular dose of epinephrine via auto-injector... Indications and usage: Epinephrine is inidcated in the emergency treatment of allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs and other allergens as well as idiopathic or exercise-induced anaphylaxis. Such reactions may occur within minutes after exposure and consist of flushing, apprehension, syncope, tachycardia, thready or unobtainable pulse with a fall in blood pressure, convulsions, vomiting, diarrhea and abdominal cramps, involuntary voiding, wheezing, dyspnea due to laryngeal spasm, pruritis, rashes, urticaria or angioedema. The EpiPen is designed as emergency supportive therapy only and is NOT a replacement or substitute for immediate medical or hospital care. There are NO absolute contraindications to the use of epinephrine in a life-threatening situation! I'd like to say that I have never needed to use one... The truth, however, is that I have never had one expire in the 15+ years that I have carried one.... Is your 101st apiary guest severly allergic and doesn't know it? I'd rather be prepared to save a friend than attend a funeral that might have been avoided or delayed.... I think that is probably enough on this subject unless one would like to state the symptoms in less medical terms I.E. common language that most might understand.. Sincerely, [log in to unmask] - Ken Adams P.S. Oh Yes...Cost? Dispensed with perscription only in USA... Complete kit is less than $40. Refill somewhat less... Larger quantities somewhat less also...Usually expiration is 18 to 24 months after purchase... Ask your MD or MD's nurse.....and Don't accept NO as an answer.....you might save a life or two!