Dear Kathy, I susually do no like to answer drug related question on a network because there are usually too many variables and confusion is easy. But topical cortizone preparation is no problem as long as the baby does not eat the cream!!!!. This is almost as bad as the case I had once of a mom told to wean because she was taking cortizone ear drops!!!. Steroids such as prednisone, more potent than cortisone are not a reason to stop BF even when taken orally! Good luck Maryelle