Fiona, Dr. Ruth Lawrence's book indicates that oral Fluconazole is safe and indicated for use in lactating mothers. I have called several drug info lines and they also indicate this. I dont think , from what I have read, that Diflucan has the same liver effects as Nizoral. I also read somewhere that they use Diflucan on NICU babies..who have thrush systemically. Therefore, we do recommend that mothers see a physician and get a prescription for this particular drug. It is safe according to the information I have derived. Kathleen >I'd be really interested to hear about other drug treatment for thrush, as >experience in my part of the world seems limited. What has worked for you? >How safe was it? > ********************************************************** Kathleen B. Bruce RN, BSN, IBCLC Williston, Vermont USA [log in to unmask] **********************************************************************