I have worked with several mothers through the years who experienced a dramatic drop in milk supply after starting the mini-pill. I have also seen it have the opposite effect of increasing a milk supply. There doesn't seem to be any predictor that I'm aware of. In general it is thought that if a trial month on the mini-pill is successful the depo-provera injection should be ok. At least if the mini-pill causes a drop in milk supply it can be stopped and the supply should rebound quickly. After the depo-provera shot there is no way to correct the problem of decreased milk supply that I am aware of. This is my first time on-line with Lact-net. My name is Denise Parker. I am IBCLC and have been associated with LLL for 15 years. I'd like to hear more on this issue. Denise