> The genetics works well in a lab but not easy in the natural world.

Well, one thing is: the people that sell bees think they are vastly improved but you rarely hear that claim from people that buy them. I have bought a lot of queens over the years and mostly they were average or less than average. Weavers stock at present seems to produce better than average and has lower than average mites. But there are no bees that produce twice as much honey or are mite proof in all regions. Compare this to gains in other livestock. Production per cow in the United States averaged about 5,000 pounds per cow in 1925 to 22,000 pounds per cow in 2012. Much of this is attributable to breeding.

PLB

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