Re: genetic basis of insecticide resistance Detoxification of pyrethroid in insects is mainly accomplished by monooxygenases, also called P450 enzymes. Over expression of one or more of these P450 genes has been associated with pyrethroid resistance in house flies [9], mosquitoes [10,11] and many other insects. Several genes related to pyrethroid resistance in pathways such as cellular and molecular metabolism, signal transduction, vesicular and molecular transport, protein biosynthesis, ubiquitination, and neuronal survival have been detected by PCR hybridization and cDNA microarray technique [13]. It has been shown that insect detoxification of pyrethriod compound is a multicellular and network function rather than the function of a single enzyme. Pesticide Biochemistry and Physiology 96 (2010) 1–7 *********************************************** The BEE-L mailing list is powered by L-Soft's renowned LISTSERV(R) list management software. For more information, go to: http://www.lsoft.com/LISTSERV-powered.html Access BEE-L directly at: http://community.lsoft.com/scripts/wa-LSOFTDONATIONS.exe?A0=BEE-L