Hello

An interesting study.


Quaghebeur A, Mutunga L, Mwanyumba F, Mandaliya K, Verhofstede C,
Temmerman M.



Low efficacy of nevirapine (HIVNET012) in preventing  perinatal HIV-1
transmission in a real-life situation. AIDS 2004 Sep 3;18:1854-1856.


International Centre for Reproductive Health, Ghent University, Ghent,
Belgium.



 Abstract: Since 2001, the unrestricted use of HIVNET012 has been
recommended for the prevention of mother-to-child transmission in
low-resource settings, despite the lack of validated efficacy data  outside
research settings. We implemented the nevirapine regimen in a  real-life
situation in Kenya. The perinatal HIV-1 transmission rate at  14 weeks was
18.1%, similar to the 21.7% before the intervention. These  data call for
further evaluation of the simple nevirapine regimen in field conditions, and
underline the need for alternative strategies.






Kindly
Françoise Railhet
Manager of the Medical Associates Program
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