Greetings All!
From France:
In: Food Chemistry 2019 May 30;281:294-303. doi: 10.1016/j.foodchem.2018.12.086. Epub 2018 Dec 28.
Title: Impact of human milk pasteurization on the kinetics of peptide release during in vitro dynamic digestion at the preterm newborn stage.
Authors: Deglaire A, Oliveira S, Jardin J, Briard-Bion V, Kroell F, Emily M, Ménard O, Bourlieu C, Dupont D.
Abstract
"Holder pasteurization (62.5 °C, 30 min) of human milk denatures beneficial proteins. The present paper aimed to assess whether this can affect the kinetics of peptide release during digestion at the preterm stage. Raw (RHM) or pasteurized (PHM) human milk were digested in triplicates using an in vitro dynamic system. Mass spectrometry and multivariate statistics were conducted. Pre-proteolysis occurred mostly on β-casein, for which cumulative peptide abundance was significantly greater in PHM over 28% of the hydrolysed sequence. Eight clusters resumed the kinetics of peptide release during digestion, which differed on seven clusters (69% of the 1134 peptides). Clusters associated to the heat-denaturated proteins, lactoferrin and bile salt-stimulated lipase, presented different kinetics of release during digestion, unlike that for β-casein. Some bioactive peptides from β-casein presented significant different abundances between PHM and RHM before digestion (1-18, 185-211) or in during intestinal digestion (154-160, 161-166). Further physiological consequences should be investigated. KEYWORDS: Digestion; Human milk; Pasteurization; Peptidomics; Preterm"
Abstract only:
https://www.sciencedirect.com/science/article/pii/S0308814618321903?via%3Dihub
From Germany:
Journal: Neonatology. 2019 Jan 15;115(3):211-216. doi: 10.1159/000494625. [Epub ahead of print]
Title: Milk Curd Obstruction in Human Milk-Fed Preterm Infants.
Authors: Longardt AC, Loui A, Bührer C, Berns M.
Abstract
"BACKGROUND: Milk curd obstruction as a cause of intestinal obstruction has been known since 1959, but has nearly disappeared. However, in recent years it has experienced a revival in small premature infants. OBJECTIVE: The aim of this study was to evaluate the clinical characteristics of milk curd obstruction (lactobezoar) in preterm infants. METHODS: Data of preterm infants with milk curd obstruction cared for at a large tertiary neonatal intensive care unit between 2012 and 2016 were retrieved from the electronic registry and paper records. RESULTS:
A total of 10 infants (2 girls, 8 boys) were identified: the median birth weight was 595 g (range 270-922), gestational age was 24.4 weeks (23.4-27.0), weight-for-gestational age percentile was 16 (0-62), and age at diagnosis was 28 days (16-64). Five infants (50%) were small for gestational age. All neonates had received fortified human milk (added protein 2.0 g/100 mL, range 0-2.8; added calcium 2,400 µmol/100 mL, range 0-6 844; added phosphate 2,400 µmol/100 mL, range 0-5,178). Seven neonates underwent surgery, and 2 infants died. Hyperechoic masses in extended bowel loops, visualised by abdominal ultrasound, and pale/acholic faeces were hallmarks of milk curd obstruction. CONCLUSIONS: In this study, milk curd obstruction occurred exclusively in infants with a birth weight < 1,000 g (2.2%) and < 28 weeks' gestational age (2.4%). Male and small for gestational age infants appeared to be at increased risk. Paying attention to the colour of the faeces of infants at risk might help to diagnose milk curd obstruction at an early stage. KEYWORDS: Fortified breast milk; Intestinal obstruction; Milk curd obstruction; Neonate; Protein"
Abstract only:
https://www.karger.com/Article/Abstract/494625
From the U.S.:
In: Pediatric Obesity 2019 Jan 10:e12503. doi: 10.1111/ijpo.12503. [Epub ahead of print]
Title: Early rapid weight gain among formula-fed infants: Impact of formula type and maternal feeding styles.
Authors: Mennella JA, Papas MA, Reiter AR, Stallings VA, Trabulsi JC.
Abstract
"BACKGROUND: What and how infants are fed are considered important determinants for the risk factor of early rapid gain weight. OBJECTIVES: We conducted secondary analyses on data from a randomized clinical trial, wherein infants randomized to feed cow milk formula had double the incidence of early rapid weight gain than those fed extensively hydrolyzed protein formula, to determine whether maternal feeding styles had independent effects or interactive effects with infant formula type on early rapid weight gain. METHODS: Anthropometry and feeding patterning (number of daily formula feeds) were measured monthly, and maternal feeding styles were measured at 0.5, 3.5, and 4.5 months. Longitudinal models were fitted using generalized estimating equations and separate logistic models conducted. RESULTS: The treatment groups did not differ in formula feeding patterning or in maternal feeding styles, which were stable across the first 4.5 months. Feeding styles had no significant effects on early rapid weight gain and did not interact with formula group. However, type of infant formula had a direct and independent impact on early rapid weight gain (P = 0.003). CONCLUSIONS: The type of infant formula had a differential impact on early rapid weight gain independent of maternal feeding style, highlighting the self-regulatory capabilities of infants. KEYWORDS: infant formula; maternal feeding styles; patterning of feeding; rapid weight gain"
Abstract only: https://onlinelibrary.wiley.com/doi/abs/10.1111/ijpo.12503
With kind regards,
Debbie
Debra Swank, RN BSN IBCLC
Program Director
More Than Reflexes Education
Ocala, Florida USA
http://www.morethanreflexes.org
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