Colostrum's composition is due to low milk production and open gap 
junctions. Once the production ramps up, more lactose is produced, 
drawing more water into the milk and increasing the volume. The more 
active cells swell, causing tight junctions to form, closing the gaps. 
This controls the ion content of the milk, and reduces/eliminates 
paracellular (between cell) transport of large chemicals and cells. So 
colostrum's different composition is due to these factors, greater 
paracellular transport and less dilution. The same components exist in 
milk and colostrum, except for things that sneak in through the gaps in 
early lactation.

Catherine Watson Genna, IBCLC  NYC

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