Copyright (c) 1995 American Academy of Pediatrics
Pediatrics 1995; 96: 148-150; July, 1995
TITLE: Persistent Hypothyroidism in an Infant Receiving a Soy Formula: Case
Report and Review of the Literature
AUTHOR: PAULA ANN CHORAZY, MD, PHD, SETH HIMELHOCH, MD, NANCY J. HOPWOOD,
MD, Department of Pediatrics, Division of Pediatric Endocrinology,
University of Michigan Medical Center, Ann Arbor, MI; NANCY G. GREGER, MD,
DANIEL C. POSTELLON, MD, Department of Pediatrics, Division of Pediatric
Endocrinology, Children's Hospital of Michigan, Detroit, MI
TEXT: Soy-induced goiter was a well-known phenomenon before 1966, the back
date used in many computerized literature databases. [n1-n4] In the
mid-1960s, iodine-supplemented infant soy formulas prepared from isolated
soy protein were introduced by commercial manufacturers. [n5] Since then,
there have not been any documented cases of soy formula-associated
hypothyroidism.
We present the case of a patient with congenital hypothyroidism who
remained persistently hypothyroid while on a soy formula diet despite large
doses of L-thyroxine (T[4]). This case made us reaware of the historical
data on the effects of soy on thyroid function...[etc.]...
...[etc.]...
Reprint requests to (N.J.H.) Department of Pediatrics, Division of
Endocrinology, University of Michigan, Room D3252, Medical Professional
Building, Ann Arbor, MI 48109-0718.
REFERENCES:
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[log in to unmask] (Arly Helm, MS, CLE, IBCLC)
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