Dear Dr. Armeni,

If this is a similar drug to Filgastim, and it almost certainly is, then it
will not get into the milk, being too large. So there is simply no issue,
none at all. Furthermore, as the oral bioavailability is zero, even if some
did get into the milk, the baby would not absorb it.
The mother should continue breastfeeding in full confidence that her baby
will not receive any of this medication.

From: "Maria Ersilia Armeni (by way of Kathleen Bruce
<[log in to unmask]>)" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Sunday, December 01, 2002 7:26 AM
Subject: Lenograstim

 > Hi. A mother nursing her 10 month old son has been identified as the best
 > bone marrow donor to her own leukemic brother. She is going to get
 > injections of a new drug, Lenograstim, a white cell colony stimulating
 > factor. Obviously she has been told to stop breastfeeding because they
 > dont' know whether it could harm her infant. I have been found some info
 > about Filgrastim in Hale, which seems to be quite a similar drug; I have
 > been trying contacting Jack Newman- did he change address? Wondering
 > whether you had some direct/indirect knowledge about this treatment and
 > its relationship to breastfeeding.
 > M.Ersilia Armeni, pediatrician, IBCLC, Roma (Italy)


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