The mother of the 2 1/2 week old does *not* plan to wean to take Zyrtec, but
*does* want to leave a 4 hour window during which she'll provide milk pumped
earlier in the day.  She started doing this when she was on prednisone, last
week.  Hale says, "following administration, wait at least 4 hours if
possible prior to feeding infant to reduce exposure," so that's what she
did.

The half-life of prednisone is 3 hours, the peak is at 1-2 hours.  The
half-life of Zyrtec is 8.3 hours, the peak is at 1.7 hours.  So I suppose,
though it may be less important to do, following the same procedure avoids
the peak of Zyrtec just as well as it avoids the peak of prednisone.

Diane Wiessinger, MS, IBCLC  Ithaca, NY

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