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Subject:
From:
Debra Swank <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Tue, 22 May 2018 02:13:29 -0400
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Greetings All,

Two new studies:  

1)  Important new study from Spain in the journal, Women and Birth:

Title:  Cessation of breastfeeding in association with oxytocin administration and type of birth

Authors:  Fernández-Cañadas Morillo A, Durán Duque M, Hernández López AB, Muriel Miguel C, Pérez Riveiro P, Salcedo Mariña A, Royuela Vicente A, Casillas Santana ML, Marín Gabriel MA

Abstract:  
"BACKGROUND: Some studies have suggested an association between synthetic oxytocin administration and type of birth with the initiation and consolidation of breastfeeding."

AIM:
"This study aimed to test whether oxytocin administration and type of birth are associated with cessation of exclusive breastfeeding at different periods. A second objective was to investigate whether the administered oxytocin dose is associated with cessation of exclusive breastfeeding."

METHODS:
"We conducted a prospective cohort study (n=529) in a tertiary hospital. Only full-term singleton pregnancies were included. Four groups were established based on the type of birth (vaginal or cesarean) and the intrapartum administration of oxytocin. Follow-up was performed to evaluate the consolidation of exclusive breastfeeding at 1, 3 and 6months."

FINDINGS:
"During follow-up, the proportion of exclusive breastfeeding decreased in all groups. After adjusting for confounding variables, the group with cesarean birth without oxytocin (planned cesarean birth) had the highest risk of cessation of exclusive breastfeeding (odds ratio [95% confidence interval], 2.51 [1.53-4.12]). No association was found between the oxytocin dose administered during birth and puerperium period and the cessation of exclusive breastfeeding."

CONCLUSION:
"Planned cesarean birth without oxytocin is associated with the cessation of exclusive breastfeeding at 1, 3 and 6months of life. It would be desirable to limit elective cesarean births to essentials as well as to give maximum support to encourage breastfeeding in this group of women. The dose of oxytocin given during birth and puerperium period is not associated with cessation of exclusive breastfeeding."

https://www.ncbi.nlm.nih.gov/pubmed/29754970


2) New open access study from Germany in the journal, Scientific Reports: 

Title:  Endogenous testosterone and exogenous oxytocin influence the response to baby schema in the female brain

Authors:  Sarah K. C. Holtfrerich, Roland Pfster, Alexander T. El Gammal, Eugen Bellon & Esther K. Diekhof

Abstract:  "Nurturing behavior may be critically influenced by the interplay of different hormones. The
neuropeptide oxytocin is known to promote maternal behavior and its reduction has been associated
with postpartum depression risk and child neglect. Contrariwise, the observed decrease in testosterone
level during early parenthood may benefit caretaking behavior, whereas increased testosterone may
reduce attention to infants. Here we used functional magnetic resonance imaging to investigate the
interactive influence of testosterone and oxytocin on selective attention to and neural processing of
the baby schema (BS). 57 nulliparous women performed a target detection task with human faces
with varying degree of BS following double-blinded placebo-controlled oxytocin administration in a
between-subjects design. Our results support the idea that oxytocin enhances attention to the BS.
Oxytocin had a positive effect on activation of the inferior frontal junction during identification of infant
targets with a high degree of BS that were presented among adult distractors. Further, activation of
the putamen was positively correlated with selective attention to the BS, but only in women with high
endogenous testosterone who received oxytocin. These findings provide initial evidence for the neural
mechanism by which oxytocin may counteract the negative effects of testosterone in the modulation of
nurturing behavior."

https://www.nature.com/articles/s41598-018-26020-4

With best regards,

Debra Swank, RN BSN IBCLC
Ocala, Florida USA
MoreThanReflexes Education
http://www.MoreThanReflexes.org

             ***********************************************

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