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Subject:
From:
"Nice, Frank (NIH/NINDS)" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Tue, 29 Apr 2003 13:25:30 -0400
Content-Type:
text/plain
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text/plain (26 lines)
The milk:plasma ratio for the drug and its metabolites is approximately 0.5.
No adverse effects have been reported.  Because the AAP finds carbamazepine
to be compatible with breastfeeding, one can assume that oxcarbazepine is
also compatible.

One can reference:

Bar-Oz B, Nulman I, Koren G, et al.  Anticonvulsants and breast feeding: a
critical review.  Pediatric Drugs 2000; 2: 113-26.
Briggs GG, Freeman RK, Yaffe SJ.  Drugs in Pregnancy and Lactation (Update)
2001; 14: 13-4.

Frank J. Nice, DPA, CPHP

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