I wonder if the yogurt was the heavily sweetened variety.?

Kathleen


-----Original Message-----
From: Lactation Information and Discussion
[mailto:[log in to unmask]] On Behalf Of Denise Fisher
Sent: Wednesday, November 03, 2004 6:00 PM
To: [log in to unmask]
Subject: lactobacillus and candida


Thought you may find this article of interest:
http://bmj.bmjjournals.com/cgi/content/full/329/7465/548

To avoid developing vulvovaginal candidiasis after antibiotic use, many
women use complementary and alternative therapies, including
lactobacillus in various forms (e.g., oral capsules, vaginal
suppositories, yogurt). In this Australian study, 278 women (age range,
18-50) with nongynecologic infections were randomized to receive one of
four regimens during 6 days of antibiotic use and 4 days thereafter: an
oral lactobacillus-containing powder (one-half teaspoon twice daily) and
a lactobacillus-containing vaginal suppository (once daily at bedtime);
oral lactobacillus and vaginal placebo; vaginal lactobacillus and oral
placebo; or double placebo.

Women completed symptom surveys and provided self-collected vaginal-swab
specimens at baseline and either 4 days after completing their
randomized treatment or when symptoms developed. Cases were defined as
women with symptoms plus candida isolated from the follow-up swab;
asymptomatic women with positive cultures were not considered cases.

The trial was terminated when enrollment was 62% complete because
interim analysis showed no evidence of treatment benefit. Of the 235
women with complete outcome data (85% of those randomized), 55 developed
symptomatic vaginal candidiasis. The incidence was 24% with oral and
vaginal lactobacillus, 24% with oral lactobacillus and vaginal placebo,
29% with vaginal lactobacillus and oral placebo, and 17% with double
placebo. The resulting odds ratios for developing candidiasis were 1.06
for oral lactobacillus and 1.38 for vaginal lactobacillus (both ORs were
nonsignificant).

Comment: Despite conventional wisdom encouraging women to use
lactobacillus preparations to prevent yeast infections after antibiotic
use, this small but well-designed study demonstrated no benefit from
this practice. In fact, the findings suggest the potential for harm.
Based on this study, clinicians should discourage patients from using
these products to prevent post-antibiotic yeast infections.


***************************************
Denise Fisher
Health e-Learning
http://www.health-e-learning.com

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