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Subject:
From:
Nikki Lee <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Fri, 28 Aug 2015 07:46:01 -0400
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Dear Lactnet Friends:

http://toxnet.nlm.nih.gov/cgi-bin/sis/search2

​"​
Summary of Use during Lactation:
Limited information indicates that maternal doses of methylergonovine up to
0.75 mg daily produce low levels in milk. Product labeling in the U.S.
currently recommends avoiding breast feeding for 12 hours following the
last dose of methylergonovine. This warning appears to be based on
unpublished adverse reactions in breastfed infants after several days of
maternal methylergonovine therapy. The use of shorter courses of the drug
after delivery during the colostral phase of lactation would not be
expected to transfer appreciable amounts of drug to the breastfed infant or
risk adverse effects in the infant. Long courses of methylergonovine,
especially after the milk comes in, are best avoided in mothers who wish to
nurse. When they are required, withholding breast feeding for 12 hours
following the last dose of methylergonovine is prudent. If adverse
reactions in the breastfed infant are seen, such as tachycardia, vomiting,
diarrhea or agitation, the drug should be discontinued. Some sources
recommend avoiding methylergonovine altogether during breastfeeding.[1]

Although results of several imperfect studies are somewhat mixed, it
appears that methylergonovine can decrease serum prolactin and possibly the
amount of milk production and duration of lactation, especially when used
in the immediate postpartum period. The effect seems to be related to the
dosage and route of administration, with injected doses having a greater
impact than oral. A few oral doses may not severely affect lactation.
​"

warmly,​


-- 
Nikki Lee RN, BSN, Mother of 2, MS, IBCLC, CCE, CIMI, ANLC, CKC
Author:* Complementary and Alternative Medicine in Breastfeeding Therapy*
www.nikkileehealth.com
https://www.facebook.com/nikkileehealth

*Get my FREE webinar series*

             ***********************************************

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