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Subject:
From:
Fiona Coombes <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Sun, 28 Mar 1999 15:17:51 +0800
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Pamela

The biochemical abnormality of polycystic ovary syndrome (PCOS) is
hyperinsulinemia. This leads to adrenal overproduction of testosterone
and
androstenedione (two androgenic [male] sex hormones). This in turn
affects
the pituitary-ovarian axis, leading to abnormal production of LH and FSH
(which stimulate the ovaries). The result of LH and FSH abnormalities is
ovarian underproduction of estrogen, along with abnormal production of
progesterone, and amenorrhea and infertility.  AS oestrogen levels are
low, it is possible that it has an effect on breast development.
Women with PCOD often have problems becoming pregnant, but I don't
know if low milk supply is much more common in these women.
Lisa Marasco, who is (?was) a Lactnetter, knows a lot about this subject.
Lisa, are you out there???


Hope this helps

Fiona




Fiona Coombes MBBS IBCLC               [log in to unmask]
Lactation Consultant, Family Physician
Perth Western Australia

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